Blog

Notes from inside the build.

What I am seeing in pharma, AI, and the work of building things people actually use.

Abstract handoff motif on white, a geometric shape passing from a grey hand silhouette into a network of teal lines

Featured· Pharma, AI

Why I Built Human in the Loop for Pharma

Pharma leaders make hundreds of decisions a week with no audit trail. Human in the Loop is the AI deployment model that makes pharma accountable.

April 29, 2026 · 4 min read

AllAIBusinessPharma
Pie chart abstraction with 70% in grey and 30% in teal, broken further into a smaller half in lighter teal

Pharma, Business

The MSL Productivity Paradox: 70% Admin, 30% Science

Medical Science Liaisons spend 70% of their time on admin. Of the 30% they spend on science, half is rework. Here is the data and the structural cause.

May 7 · 3 min read

Abstract layered briefing document on white, with one transparent layer highlighted in teal

AI, Business, Pharma

How to Brief an AI Agent Like a Senior Partner: A Pharma Operator's Framework

Most pharma teams brief AI agents like search engines. The teams getting results brief them like senior associates. Here is the framework that changes the output.

May 6 · 3 min read

Two abstract human figures rendered in grey on a white background, with a single figure highlighted in teal among a much smaller cluster

Pharma, Business

The Field Force Reckoning: Why Pharma Is Cutting 50% of Its Reps by 2028

Pfizer cut 7,500 reps in 2024. Bayer announced 1,500 in early 2026. Sanofi cut 800 in March. The era of the 600-rep field force is ending. Here is what is replacing it.

May 5 · 3 min read

Abstract funnel on white background with patient dots flowing through, most falling away in grey, one continuing in teal

Pharma, Business

The Patient Your Pharma Forecast Forgot

Pharma forecasts are built in three stages by three different teams. The third arrives too late to change anything. Here is why and what to fix.

Apr 15 · 3 min read

Two abstract upward trajectory lines diverging on a white background, one continuing to rise in teal and one declining in grey

Pharma, Business

Why 66% of Drug Launches Miss Their Forecast in 2026

Two thirds of pharma drug launches miss first year sales targets. The real reason is not the molecule. It is the commercial system around it.

Mar 25 · 3 min read

Get new posts in your inbox.

No spam. No funnel sequences. Just new writing when it ships.

Unsubscribe anytime. Your email is never sold.