Blog

Notes from inside the build.

What I am seeing in pharma, AI, and the work of building things people actually use.

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Pharma, AI

The Audit Trail Problem: Why Pharma's AI Deployments Will Face FDA Scrutiny by 2027

The FDA issued 40 untitled letters in a single day in September 2025. The next enforcement wave will target AI-driven decisions without audit trails. Here is why your pharma company needs to act now.

May 11 · 3 min read

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AI, Pharma

Why Pharma's Best AI Bets Are Boring (And Why That's the Point)

The AI investments that will define pharma's next decade are not the flashy ones. They are the boring ones. Here is what to look for and why your CFO will not approve them.

May 10 · 3 min read

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Pharma, Business

The MSL Productivity Paradox: 70% Admin, 30% Science

Medical Science Liaisons spend 70% of their time on admin. Of the 30% they spend on science, half is rework. Here is the data and the structural cause.

May 7 · 3 min read

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AI, Business, Pharma

How to Brief an AI Agent Like a Senior Partner: A Pharma Operator's Framework

Most pharma teams brief AI agents like search engines. The teams getting results brief them like senior associates. Here is the framework that changes the output.

May 6 · 3 min read

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Pharma, Business

The Field Force Reckoning: Why Pharma Is Cutting 50% of Its Reps by 2028

Pfizer cut 7,500 reps in 2024. Bayer announced 1,500 in early 2026. Sanofi cut 800 in March. The era of the 600-rep field force is ending. Here is what is replacing it.

May 5 · 3 min read

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Pharma, AI

Why I Built Human in the Loop for Pharma

Pharma leaders make hundreds of decisions a week with no audit trail. Human in the Loop is the AI deployment model that makes pharma accountable.

Apr 29 · 3 min read

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Pharma, Business

The Patient Your Pharma Forecast Forgot

Pharma forecasts are built in three stages by three different teams. The third arrives too late to change anything. Here is why and what to fix.

Apr 15 · 3 min read

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Pharma, AI

AI in Pharma Is an Architecture Decision, Not a Procurement One

Most pharma boardrooms ask which AI model to buy. The companies winning are asking which architecture to build. Here is why that matters.

Apr 8 · 3 min read

all of grey rectangles representing ignored pharma emails with a single rectangle highlighted in teal

Pharma, AI

Pharma Spends $6.2B on HCP Marketing. 97% Gets Ignored.

Pharma spent 6.2 billion dollars on HCP digital marketing in 2025. 97 percent of it got ignored. Here is the data and what actually works.

Apr 1 · 3 min read

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Pharma, Business

Why 66% of Drug Launches Miss Their Forecast in 2026

Two thirds of pharma drug launches miss first year sales targets. The real reason is not the molecule. It is the commercial system around it.

Mar 25 · 3 min read

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